A laboratory co-culture of cardiomyocytes derived from human induced pluripotent stem cells and sympathetic nerve cells was reported to form a physical connection in a compartmentalized microfluidic device. The cells showed electrical and beating-rate responses to nicotine and propranolol, offering preliminary platform evidence for neuro-cardiac research.
In 1,198 non-shockable out-of-hospital cardiac arrests, 13.9% had any documented return of spontaneous circulation and 12.2% maintained it through EMS care. Witnessed arrests and PEA were associated with higher odds in adjusted models, while the study could not establish cause and effect.
International journal of emergency medicine4 min read
Among people with hypertension, esaxerenone was associated with fewer cardiovascular events than spironolactone, with the gap concentrated in heart failure and atrial fibrillation.