Airway HDAC2 and HDAC8 expression differed between COPD patients who did and did not respond to inhaled corticosteroids, with findings in airway smooth muscle and other tissue compartments. The analysis cannot show that either protein causes treatment response.
A single-center retrospective cohort of 68 hospitalized adults found similar initial presentation and severity scores but longer hospital stays and higher 90-day mortality among patients with culture-confirmed community-acquired E. coli pneumonia than among those with other culture-confirmed CAP.
A Seoul analysis of daily health-service counts for people under 19 found that ambient VOC mixtures were associated with higher outpatient visits and hospital admissions for atopic dermatitis and asthma. Toluene carried the highest mixture weight for both outcomes, while scenario-based burden estimates depended on a hypothetical lower-exposure benchmark.
Journal of exposure science & environmental epidemiology3 min read
A five-patient paired PET/CT study found that two FAPI tracers looked similar across most assessed tissues, but one showed higher uptake in blood, spleen and small bowel.
A randomized trial of 90 adults with upper respiratory tract scleroma found more short-term clinical improvement after three months of levofloxacin than after third-generation cephalosporins, though the study was small, single-center and too brief to assess relapse.
Among 60 adults undergoing airway surgery for laryngotracheal stenosis, those with missed visits were more likely to remain tracheostomy dependent, while other social and clinical differences were not statistically clear.
Laryngoscope investigative otolaryngology4 min read